Many new
studies on apple polyphenols are now available online. Please check the
following sections for a review of the latest posted research:
allergies,
skin cancer,
heart disease, and
cholesterol.
Research into the health
benefits of apple polyphenol
extracts has accelerated in recent months, and an impressive body
of studies is now available.
Apple polyphenol extracts
are a potent scavenger of the hydroxyl radical, the most damaging type of
free radicals in your body.
One of the most exciting
findings on apple polyphenol
extracts is their ability to
dramatically increase the activity of SOD and GP, two vital intracellular free
radical scavengers.
As new research is
announced, you can be notified through the AP Science news bulletin. Just
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Why are Free Radicals Important?
As you review all of the medical studies on
apple polyphenols
(links at left, and below) you will find a common thread: their potent antioxidant
activity. The underlying mechanism of human diseases is increasingly
understood to be involved with free radical damage at the cellular level.
Since the 1950's, when Denham Harman, M.D. first proposed the
free radical theory of aging and disease, an overwhelming amount of
scientific research has investigated free radical damage as a factor in
disease. A current search of
PubMed
(the public database of the National Library of Medicine) for "free radicals
and disease" returns over 10,300 related studies.
In a recent
interview, Dr.
Harman said this: "Free-radical
reactions are implicated in 50 disorders. These 'free radical diseases'
include cancer, heart attacks, strokes, rheumatoid arthritis, cataracts, and
Alzheimer's disease -- the major cause of admission to nursing homes. The
list keeps growing."
Which Free Radicals are Most Important?
In their landmark 1983 book Life Extension: A Practical Scientific
Approach, authors Durk Pearson and Sandy Shaw identify the hydroxyl radical is "the most
dangerous type of free radical."
"Hydroxyl
radicals, the most potent oxidant known, can attack any organic substance
found in cells," say Pearson and Shaw. "They account for a large part of the
damage done by radiation..."
Shaw and Pearson also identify two key enzymes,
SOD (superoxide dismutase)
and glutathione peroxidase, as
critical antioxidant defense systems in the body. "Without these enzymes,"
they state, "you would quickly die."
In an article
published in
the British Medical
Bulletin, authors Cheeseman and Slater state that "the most important
reactants in free radical biochemistry inaerobic cells are
oxygen and its radical derivatives (superoxide andhydroxyl
radical)."
So What Does That Have to Do with Baby Apple Skins?
Apple
polyphenol extracts have been shown to deactivate or "quench" the
most damaging types of radicals known, including hydroxyl radicals,
superoxide radicals, and oxygen singlet radicals.
They have also been proven to significantly and
dramatically enhance the body's two key enzymes-
SOD and
glutathione peroxidase- that
scavenge damaging free radicals
Apple
polyphenol extracts are the only compounds in the medical literature
have shown this full range of effects against the most damaging types of
oxidative stress.
Specific Medical Studies
Relevant scientific studies on
apple polyphenols
are organized here by specific medical condition. These links are also
available from every page by the links to your left.
As soon as new studies are published, you will find them
here at applepolyphenols.com. To make it even easier for you to receive the
latest information, we have created the AP Science news bulletin. Sign up
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articles, and available products related to
apple polyphenols.
